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What Is BOTOX?
BOTOX (Botulinum Toxin Type A) Purified Neurotoxin Complex is a protein
produced by the bacterium Clostridium botulinum. The effects of
botulinum have been known since the turn of the century, but not until 1980 was
the toxin found to be therapeutically valuable for a number of ophthalmologic
disorders.
How Does It Work?
Botulinum toxin is a nerve impulse "blocker". It binds to nerve
endings and prevents the release of chemical transmitters that activate muscles.

These chemicals carry the "message" from the brain that causes a muscle to
contract; if the message is blocked, the muscle doesn't spasm.
Botulinum toxin usually takes full effect within one to two weeks.
However, the nerve endings usually grow new connections to the muscles at sites
that have not been exposed to botulinum toxin. Therefore, treatment must
be repeated as directed.
Is It Safe?
BOTOX (Botulinum Toxin Type A) Purified Neurotoxin Complex has been
recognized by the American Academy of Neurology, American Academy of
Ophthalmology and National Institutes of Health as a safe and effective treatment
for blepharospasm associated with dystonia.
Over ten years of clinical experience involving thousands of patients are a
testimony to the potential benefits of this treatment.
It is important to understand that BOTOX is an effective, ongoing treatment
for the relief of symptoms only -- it is not a cure. And, because every
patient is different, the degree of relief will vary from person to person.
Patients who have been sedentary for a long time should resume activity
slowly and carefully following the administration of BOTOX.
As with any therapeutic, certain patients may experience side effects from
the administration of BOTOX. The side effects most frequently experienced
by patients are: drooping of the eyelid (ptosis) -- 11%; irritation of the
injected area or tearing, including dry eye, opening of the eyelid (lagophtalomos)
and sensitivity to light (photophobia) -- 10%; or an outward or inward turning
of the eyelid (ectropion or entropion, respectively), inflammation of the cornea
(keratitis), or "double vision" (diplopia) -- less than 1%. These side
effects are usually transient in nature and BOTOX is generally well-tolerated by
patients.
In addition, the effects of BOTOX may be increased with the use of certain
antibiotics or other drugs that interfere with neuromuscular transmission.
Ask your doctor if any of your current medication(s) interact with BOTOX.
If you have any questions regarding the use of BOTOX treatment, please
consult your doctor.

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